Clinical TMS Society, Inc.
4747 N. First Street, Suite 140
Fresno, CA 93726
(845) 392-3238 • (559) 227-1463


 

TMS Therapy

About TMS Therapy

Since the 1980s, Transcranial Magnetic Stimulation (TMS) has been used to study the nerve fibers that carry information about movements from the brain to the spinal cord and on to the muscles. In the late 1990s, physicians began to explore the therapeutic potential of TMS for the treatment of a variety of diseases, with depression being the most thoroughly studied to date. Since then, more than 20 randomized, controlled trials studying TMS as a treatment for depression have been published by researchers throughout the world.

TMS Therapy is:

· Non-invasive, meaning that it does not involve surgery. It does not require any anesthesia or sedation, as the patient remains awake and alert during the treatment.

· Non-systemic, meaning that it is not taken by mouth and does not circulate in the bloodstream throughout the body.

Brainsway Deep TMS

In January 2013, the FDA approved Deep TMS therapy developed by Brainsway for the treatment of depressive episodes in adult patients suffering from Major Depressive Disorder, who failed to achieve satisfactory improvement from any number of previous antidepressant medication treatment in the current episode. Deep TMS has been used in several other countries and is under investigation for several other conditions.

 

Magstim

Magstim are the pioneers of Transcranial Magnetic Stimulation technology, bringing over 25 years of experience into clinical practice. In May 2015, Magstim received FDA 510 (k) clearance to market its Rapid2 Therapy System for the treatment of Major Depressive Disorder in adult patients who have failed to achieve satisfactory improvement from prior antidepressant medication in the current episode.

 

Magvita TMS Therapy

On July 31st, 2015, MagVenture received FDA 510(k) clearance to market the MagVita TMS Therapy® system for Major Depressive Disorder. MagVita TMS Therapy is indicated for adult patients who have failed to receive satisfactory improvement from prior antidepressant medication in the current episode. In 2011, MagVenture’s MagVita TMS therapy System was the first to receive a European clearance.

 

Neurostar TMS Therapy

In October 2008, the FDA approved TMS Therapy using the NeuroStar TMS brain-stimulating device for patients suffering from Major Depressive Disorder who have failed to achieve satisfactory improvement from antidepressant treatment. Neuronetics pioneered clinical TMS practice in the US with almost 500 practices. They played a pivotal role in educating the public and clinicians on TMS and advocating for insurance coverage in several states.

 

How Does TMS Work?

Through a treatment coil, the TMS Therapy system generates highly concentrated, magnetic fields which are rapidly switched on and off. These magnetic fields do not directly affect the whole brain; they only reach a few centimeters into the brain, directly beneath the treatment coil.

The treatment coil is applied to the head above the left prefrontal cortex. This part of the brain is involved with mood regulation and therefore, is the location where the magnetic fields are focused. These magnetic fields do not directly affect the whole brain; they only reach about 2-3 centimeters into the brain directly beneath the treatment coil. As these magnetic fields move into the brain, they produce very small electrical currents. These electrical currents activate cells within the brain which are thought to release neurotransmitters like serotonin, norepinephrine, and dopamine to treat depression.

Non-invasive, meaning that it does not involve surgery. It does not require any anesthesia or sedation, as the patient remains awake and alert during the treatment.Non-systemic, meaning that it is not taken by mouth and does not circulate in the bloodstream throughout the body.