The Clinical TMS Society presents this installment of our Grand Rounds Webinar Series: Controlling Brain State Variability to Optimize rTMS Efficacy featuring Speaker: Lysianne Beynel, PhD
In this presentation, we will explore the pivotal role of brain state variability in influencing basic TMS outcomes like MEP and phosphenes. We will then focus on some clinical applications that used control of state-dependency as a proof of principle. Finally, in a demonstration of a specific case of state-dependency control, we will uncover the potential synergy between rTMS and cognitive therapy in
improving depression treatment, as a way to pave the way for more personalized and effective therapies.
At the end of this presentation participants will be able to:
• Demonstrate how varying brain states affect basic TMS measures like motor
evoked potentials (MEPs) and phosphenes.
• Evaluate the impact of controlling brain state on improving rTMS outcomes as
a proof of principle.
• Examine the potential benefits of combining rTMS with cognitive therapy for
treating depression in this context.
Take advantage of our live Q&A session at the conclusion of the webinar!
1 Hour CME Credit available
Format: On-Demand
Cost: Members: $25 | Non-members $50 | Student Members FREE
Speaker: Lysianne Beynel, PhD
Dr. Beynel completed her PhD at University Grenoble Alpes in France where she
investigated the effects of transcranial magnetic stimulation (TMS) on bipolar
disorders. She then moved to Duke University for her post-doc work, where she
investigated the use of rTMS in improving working memory in older adults. Her
research, at that time, was mainly focused on the effects of ‘online’ TMS, i.e., applying
stimulation while participants were performing a task, as a potential means to further
engage the stimulated network and produce stronger effect. She is now a Research
Fellow at the NonInvasive Neuromodulation Unit (NNU) in the Experimental
Therapeutics and Pathophysiology Branch of the National Institute of Mental Health,
where she is combines two of these skill sets to apply TMS during cognitive therapy to
improve outcomes in depressive disorders. Dr. Beynel is also exploring the potential
of combining real-time fMRI neurofeedback with rTMS to achieve more precise control
over brain state.